Context

Most commercial lateral flow assays use a single detection area. Structuring techniques adaptable for various types of lateral flow papers are developed for multiplex sensing.

The collaborative project DiaFev furthermore aims at the integration of anti-body free point-of care tests in case of fever in order to reduce the overuse of antibiotics.

Solution

Multiplex paper-based microfluidic systems

• Design and fabrication of paper-based microfluidic circuits
• Paper structuring techniques
• Microfluidic flow studies

Demonstrator developments towards point-of-care applications

• Mastering structuring techniques of lateral flow papers
• Device integration for multiplex sensing

Advantages

• Structuring techniques for multiplex sensor developments

The developed competences in structuring techniques are transferable to the development of industrial pilot lines.

Conference presentations :

[1] E. Condemi, C. Tematio, N. Fosso, K. Nicolet, L. Jeandupeux, A. Homsy, S. Schintke, and J.-M. Segura, Towards a rapid and quantitative point-of-care test for the differential diagnosis of fever, Medi-Labo-Tech 2017, Congrès SGKC/SSCC, 30 August - 1 September 2017, Lausanne, Switzerland.

[2] E. Condemi, C. Tematio, N. Fosso, K. Nicolet, L. Jeandupeux, A. Homsy, S. Schintke, and J.-M. Segura, Towards a rapid and quantitative point-of-care test for the differential diagnosis of fever, Swiss Symposium on point of care Diagnostics, 30 September 2017, Sion, Switzerland.

Contact at HEIG-VD: Prof. Dr. Silvia Schintke

Acknowledgement: This work has been financially supported by HES-SO Thematic Programme Diagnostic Bio